Development of Colorimetric Microtiter Plate Assay for Assessment of Antimicrobials against Acanthamoeba

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Development of colorimetric microtiter plate assay for assessment of antimicrobials against Acanthamoeba.

We have developed and optimized a 96-well microtiter plate assay, based on the reduction of alamarBlue, to assess the efficacies of much needed new antimicrobials against Acanthamoeba species. This assay has been optimized for determination of drug efficacy against two potentially pathogenic species, Acanthamoeba castellanii and Acanthamoeba polyphaga, and has been validated by comparison of th...

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ژورنال

عنوان ژورنال: Journal of Clinical Microbiology

سال: 2005

ISSN: 0095-1137,1098-660X

DOI: 10.1128/jcm.43.2.629-634.2005